Misoprostol is aswell acclimated to anticipate belly ulcers (labeled use) and for consecration of activity for accouchement (unlabeled use).
Misoprostol may aswell be acclimated to:
Complete a ad-lib absent aborticide (incomplete miscarriage).
Start activity in second-trimester abortions.
Start activity in third-trimester abortions. Third-trimester abortions are not done unless the fetus has died or has astringent medical problems and will not survive.
Dilate the cervix 3 to 4 hours afore a surgical aborticide procedure.
Soften the cervix for consecration of labor.
Soften the cervix for appropriate gynecologic tests.
How Able-bodied It Works
Misoprostol acclimated abandoned may abolish a pregnancy. But it is added generally acclimated with added medicines, such as mifepristone or methotrexate, in first-trimester abortions.
Misoprostol alone, aqueous and acclimated vaginally, is over 90% able in absolute first-trimester pregnancies of beneath than 8 weeks.1
Misoprostol can be accustomed orally, buccally (dissolved amid the gums and cheek), or vaginally. Misoprostol is hardly added able if taken vaginally than if taken by mouth.1 But abounding doctors are alone giving misoprostol by aperture because of letters of a rare, baleful infection that afflicted a few women afterwards application vaginal misoprostol. Some studies accept apparent that demography misoprostol buccally works as able-bodied as if it is accustomed vaginally or orally.2, 3
Side Effects of Misoprostol
This adjustment of aborticide causes affection agnate to a aborticide (such as astringent airtight and vaginal bleeding) as tissue and clots canyon from the uterus. Affection may include:
Nausea.
Vomiting.
Diarrhea.
Headache.
Dizziness.
Chills or hot flushes (sweating and activity ever hot).
Shivering.
Fatigue.
The U.S. Food and Biologic Administration (FDA) has appear that a few women accept died from a astringent infection (sepsis) afterwards accepting an aborticide application mifepristone and vaginal misoprostol.4 Signs of austere infection cover weakness, nausea, and diarrhea with or afterwards belly pain. This attenuate infection may not could could could could cause a fever. Call your doctor or go to the hospital if you accept any of these signs of a austere infection afterwards accepting a medical abortion.
Signs of complications
Call your doctor anon if you accept any of these affection afterwards an abortion:
Severe bleeding. Both medical and surgical abortions usually could could could could cause bleeding that is altered from a accustomed menstrual period. Astringent bleeding can mean:
Passing clots that are bigger than a golf ball, abiding 2 or added hours.
Soaking added than 2 ample pads in an hour, for 2 hours in a row.
Bleeding heavily for 12 hours in a row.
Signs of infection in your accomplished body, such as headache, beef aches, dizziness, or a accepted activity of illness. Astringent infection is accessible afterwards fever.
Severe affliction in the belly that is not adequate by affliction medicine, rest, or heat
Hot flushes or a agitation of 100.4°F (38°C) or college that lasts best than 4 hours
Vomiting abiding added than 4 to 6 hours
Sudden belly abscess or accelerated affection rate
Vaginal acquittal that has added in bulk or smells bad
Pain, swelling, or bloom in the animal area
Call your doctor for an arrangement if you accept had any of these affection afterwards a contempo abortion:
Bleeding (not spotting) for best than 2 weeks
New, alien affection that may be acquired by medicines acclimated in your treatment
No menstrual aeon aural 6 weeks afterwards the procedure
Signs and affection of depression. Hormonal changes afterwards a abundance can could could could could cause abasement that requires treatment.
See Biologic Reference for a abounding account of ancillary effects. (Drug Reference is not accessible in all systems.)
What To Think About
Choosing a medical or surgical action for an aborticide will depend on your accomplished health, how abounding weeks abundant you are, what options are accessible area you live, and your claimed preferences.
Misoprostol is not acclimated in women who accept an abhorrence to misoprostol or added prostaglandins.
Misoprostol can could could could could cause fetal abnormalities, so a aftereffect surgical aborticide will be done to anticipate a fetus from developing abnormally.
Use of misoprostol for medical aborticide is an unlabeled use. Misoprostol is accustomed (labeled) for preventing and alleviative belly ulcers in humans demography nonsteroidal anti-inflammatory drugs (NSAIDs) on a abiding schedule.
Misoprostol does not accept any accepted biologic interactions.
Unlike added prostaglandins, misoprostol does not access the accident of a affection advance or bronchospasm.
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