Kucha tea, a accustomed antecedent of theacrine, has been captivated in China for bags of years afterwards any actively appear ancillary effects. However, one extraction on mice begin that top doses of theacrine decreased the yohimbine burning toxicity beginning and added head-twitching induced by 5-HTP in mice. A decreased toxicity beginning indicates that beneath yohimbine was appropriate to ability toxicity compared to the ascendancy accumulation and the added arch twitching is acceptable due to how theacrine acts on gamma-Aminobutyric acid (GABA) receptors.
Another extraction begin that theacrine added sleeping time afterwards mice were injected with pentobarbital, a short-acting barbiturate. However, we should not jump to the cessation that theacrine has almighty allaying and anesthetic backdrop based on what the extraction suggests. Given the deluge of allowances and basal cogent ancillary effects, there's no acumen not to cover Theacrine in your supplement arsenal.