Molecular Formula: C18H15Cl3N2O
Molecular Weight: 381.69
Econazole is an antifungal medication accompanying to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal bacilli from bearing basic substances appropriate for advance and function. This medication is able alone for infections acquired by fungal organisms. It will not plan for bacterial or viral infections.
Econazole interacts with 14-α demethylase, a cytochrome P-450 agitator all-important to catechumen lanosterol to ergosterol. As ergosterol is an essential basic of the fungal corpuscle membrane, inhibition of its amalgam after-effects in added cellular permeability causing arising of cellular contents. Econazole may aswell arrest autogenous respiration, collaborate with film phospholipids, arrest the transformation of yeasts to mycelial forms, arrest purine uptake, and blemish triglyceride and/or phospholipid biosynthesis.
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